drugset / Trial / NCT02951637
Chemotherapy Plus Gefitinib for Advanced Lung Adenocarcinoma and Sensitive EGFR Mutations: a Randomized Controlled Trial
Phase 2
Unknown
300 enrolled
Shanghai Chest Hospital
Changhai Hospital · collabRuijin Hospital · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to compare chemotherapy and gefitinib in combination with gefitinib alone as first-line therapy for adenocarcinoma, in terms of efficacy and safety.
Timeline
- Start
- 2016-12
- Primary completion
- 2018-04
- Completion
- 2019-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carboplatin | Small molecule | — | — |
| Subject | Gefitinib | Small molecule | 250 mg | — |
| Subject | Pemetrexed | Small molecule | 500 mg/m2 | — |