The Synergistic Effect of Dexmedetomidine on Propofol for Sedation for Pediatric Endoscopy

Phase 4 Completed 39 enrolled Keira Mason

RandomizedParallel-groupOpen-labelTreatment

Summary

The primary aim of this study is to compare the propofol requirements of children who receive propofol with that of children who receive dexmedetomidine prior to propofol, for sedation for upper and lower endoscopic procedures.

Timeline

Start: 2018-05-11
Primary completion: 2019-09-11
Completion: 2019-09-12

Publications

Mason KP, Park RS, Sullivan CA, Lukovits K, Halpin EM, Imbrescia ST, Cavanaugh D, Prescilla R, Fox VL. The synergistic effect of dexmedetomidine on propofol for paediatric deep sedation: A randomised trial. Eur J Anaesthesiol. 2021 May 1;38(5):541-547. doi: 10.1097/EJA.0000000000001350.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexmedetomidine	Other / unclassified	0.15 ug/kg	—
Comparator	Propofol	Small molecule	200 ug/kg	Intravenous

Indications

No indication recorded.