drugset / Trial / NCT02953015

Non-pharmacological Management of Chronic Migraine

NCT02953015

RandomizedParallel-groupSingle-blindTreatment

Summary

Chronic migraine (CM) is a very disabling disorder with grave socioeconomic consequences. Pharmacological approaches can affect mechanisms of pain production, while rehabilitation such as Transcutaneous Electrical Nerve Stimulation and Manual Therapy may reduce the neuromuscular contributing factors. The main aim of the study is to evaluate the effects of cervical and thoracic manipulative techniques combined with OnabotulinumtoxinA prophylaxis on headache frequency in patients with Chronic Migraine (CM). The second aim is to evaluate the training effects on the intensity of headache attacks, analgesic consumption, cervical range of motion, TrPs sensitivity and disability. The hypothesis is that the manipulative treatment would alleviate CM symptoms and, in turn, decrease the analgesic consumption.

Timeline

Start
2016-01
Primary completion
2016-09
Completion
2017-12

Drugs

EvaluationDrugModalityDoseRoute
Background Botulinum toxin type A Protein / enzyme biologic 155 iu

Indications