drugset / Trial / NCT02956044
Interaction of Bexagliflozin With Metformin, Glimepiride and Sitagliptin
RandomizedCrossoverOpen-labelTreatment
Summary
The purpose of this study is to examine the drug-drug interaction in your body when given the study drug, bexagliflozin, with three commonly used ant-diabetic medications, metformin, glimepiride or sitagliptin. The study will also evaluate how safe the study drug is and how well the study drug is tolerated when taken with metformin, glimepiride or sitagliptin.
Timeline
- Start
- 2016-11
- Primary completion
- 2017-03
- Completion
- 2017-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bexagliflozin | Small molecule | 20 mg | — |
| Comparator | Glimepiride | Small molecule | 2 mg | Oral |
| Comparator | Glimepiride | Small molecule | 4 mg | Oral |
| Comparator | Metformin | Small molecule | 1000 mg | Oral |
| Comparator | Sitagliptin | Small molecule | 100 mg | Oral |