drugset / Trial / NCT02956447
Administration of Kisspeptin in Patients With Hyperprolactinemia
Non-randomizedSequentialOpen-labelTreatment
Summary
The goal of this study is to learn more about how kisspeptin, a naturally occurring hormone, affects women with high levels of prolactin (also called hyperprolactinemia). Subjects in one group will undergo blood sampling every 10 minutes over two 12-hour periods (one 12-hour period without any intervention and one 12-hour period with intravenous (IV) kisspeptin administration). Subjects in the second group will receive subcutaneous (SC) kisspeptin every 90 minutes for eight days.
Timeline
- Start
- 2017-11-17
- Primary completion
- 2023-06-28
- Completion
- 2023-07-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gonadorelin | Protein / enzyme biologic | 0.075 ug/kg | Intravenous |
| Subject | kisspeptin 112-121 | Peptide | 0.313 ug/kg | Intravenous |
| Subject | kisspeptin 112-121 | Peptide | 2 ug/kg | Intravenous |