Botulinum Toxin Type A in Preventing Complications After Surgery in Patients With Esophageal Cancer

Summary

This randomized phase II trial studies how well botulinum toxin type A works in preventing complication after surgery in patients with esophageal cancer. Botulinum toxin type A may cause less complications of nausea and vomiting after surgery.

Timeline

Start

2016-12-30

Primary completion

2022-01-28

Completion

2022-04-28

Outcome

Missed primary endpoint

registry analysis (superiority test); Arm I (Botulinum Toxin Type A, Esophagectomy) vs Arm II (Esophagectomy); p = 0.773; Cochran-Mantel-Haenszel NCT02965976 ↗

Drugs

Indications