drugset / Trial / NCT02976727
Efficacy of Topical Calcipotriol-assisted AFL-PDT in Actinic Keratosis
RandomizedFactorialTriple-blindTreatment
Summary
Vitamin D(Vit D) is a pro-differentiation agent that enhances the accumulation of protoporphyrin IX (PpIX) after MAL(methyl-aminolevulinate) incubation in actinic keratosis and may have significant benefit for the treatment of actinic keratosis by ablative fractional laser-primed photodynamic therapy (AFL-PDT).
Timeline
- Start
- 2014-05
- Primary completion
- 2015-08
- Completion
- 2015-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Calcipotriol | Small molecule | 50 unknown | Topical |
| Background | lidocaine/prilocaine | Unknown | 5 % | Topical |
| Background | methyl aminolevulinate | Small molecule | — | Topical |