drugset / Trial / NCT02980991

Pemetrexed and Platinum Use in the Neoadjuvant Setting for Resectable Stage II and IIIA Lung Adenocarcinoma (ECTOP-1002)

NCT02980991 ↗

Phase 2 Completed 80 enrolled Fudan University
NaSingle-groupOpen-labelTreatment

Summary

This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1002. The study is a prospective, single-center, open-label, single-armed, phase II clinical trial. The aim of the study is to evaluate the radiological response rate (RR) of 2 cycles of neoadjuvant chemotherapy with pemetrexed and cisplatin in patients with resectable stage II and IIIA lung adenocarcinoma.

Timeline

Start
2015-12
Primary completion
2018-01
Completion
2018-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified 25 mg/m2 —
Subject Cisplatin Other / unclassified 75 mg/m2 —
Subject Pemetrexed Small molecule 500 mg/m2 —

Indications