drugset / Trial / NCT02983890

Dicloxacillin: Clinical Relevance of Drug-drug Interactions by Induction of Drug Metabolism.

NCT02983890

Phase 1 Completed 12 enrolled Per Damkier
RandomizedCrossoverOpen-labelTreatment

Summary

This trial is conducted as a cocktail-study namely an open-label, randomized, two-sequence, two-period crossover, cocktail study where a combination of cocktail-drugs is used to illustrate whether or not, or to what degree dicloxacillin affects the level of activity of the 5 most important CYP enzymes and therefore plays a potentially decisive role in serious drug-drug interactions.

Timeline

Start
2016-10-06
Primary completion
2017-04-05
Completion
2017-10-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dicloxacillin Small molecule 500 mg

Indications

No indication recorded.