drugset / Trial / NCT02984501

Study of Induction Chemotherapy Followed by Radiochemotherapy in Locally Advanced Pancreatic Cancer

NCT02984501 ↗

Phase 2 Completed 41 enrolled Campus-Bio-Medico University
NaSingle-groupOpen-labelTreatment

Summary

There is no a clear consensus regarding the optimal treatment of locally advanced pancreatic disease. There is a potential role for neoadjuvant therapy to treat micrometastatic disease with chemotherapy, as well as for the treatment of local disease with radiotherapy. The investigators evaluated the safety and efficacy of induction chemotherapy with oxaliplatin and gemcitabine followed by a high weekly dose of gemcitabine concurrent to radiation therapy in patients with borderline resectable and unresectable locally advanced pancreatic cancer

Timeline

Start
2013-03
Primary completion
2016-08
Completion
2016-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Chemotherapy Unknown 600 mg/m2 —
Subject Oxaliplatin Small molecule 100 mg/m2 —