drugset / Trial / NCT02986880
Effect of Type-A Botulinum Toxin in the Post-radiosurgical Neck Contractures
RandomizedParallel-groupTriple-blindTreatment
Summary
The main objective of the study is to estimate the efficiency and to determine the optimal dose of Botulinum toxin A, administered by intramuscular way in cervical spasms after radiotherapy, as well as the optimal sites for these injections. The concerned muscular groups are the sternocleidomastoid (SCM), the trapezius muscle and the splenius capitis.
Timeline
- Start
- 2011-06
- Primary completion
- 2014-01-10
- Completion
- 2014-01-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 30 iu | Intramuscular |
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 60 iu | Intramuscular |
| Subject | Botulinum toxin type A | Protein / enzyme biologic | 100 iu | Intramuscular |