drugset / Trial / NCT02996058

Safety And Efficacy Of Dexmedetomidine Sedation In Intubated Mechanically Ventilated Infants With Respiratory Failure

NCT02996058

Phase 2/3 Completed 40 enrolled Assiut University
RandomizedParallel-groupDouble-blindTreatment

Summary

Dexmedetomidine is a highly selective α2-agonist with hypnotic, analgesic, and anxiolytic properties. Despite off-label administration, dexmedetomidine has found a niche in critically ill mechanically ventilated neonates and infants because of its minimal effects on respiratory function at sedative doses, facilitating early extubation and fast-track postoperative care.

Timeline

Start
2016-12
Primary completion
2018-03
Completion
2018-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexmedetomidine Other / unclassified 0.35 ug/kg
Comparator Dexmedetomidine Other / unclassified 0.5 ug/kg

Indications

No indication recorded.