drugset / Trial / NCT02996058
Safety And Efficacy Of Dexmedetomidine Sedation In Intubated Mechanically Ventilated Infants With Respiratory Failure
RandomizedParallel-groupDouble-blindTreatment
Summary
Dexmedetomidine is a highly selective α2-agonist with hypnotic, analgesic, and anxiolytic properties. Despite off-label administration, dexmedetomidine has found a niche in critically ill mechanically ventilated neonates and infants because of its minimal effects on respiratory function at sedative doses, facilitating early extubation and fast-track postoperative care.
Timeline
- Start
- 2016-12
- Primary completion
- 2018-03
- Completion
- 2018-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | 0.35 ug/kg | — |
| Comparator | Dexmedetomidine | Other / unclassified | 0.5 ug/kg | — |
Indications
No indication recorded.