drugset / Trial / NCT03004196

Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans

NCT03004196

Phase 1/2 Completed 30 enrolled Peoples University, Bhanpur, Bhopal
RandomizedParallel-groupSingle-blindPrevention

Summary

Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures ultimately resulting in improvised standard of patient care. These bacteria metabolize different kind of carbohydrates accumulated around orthodontic appliances and create acidic environment in the oral cavity leading to enamel demineralization around the brackets and white spot lesions. This study was carried out to evaluate and compare the efficacy of probiotic toothpaste and chlorhexidine mouthwash in patients undergoing orthodontic treatment with individuals who are not using them.

Timeline

Start
2015-09
Primary completion
2015-10
Completion
2015-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Chlorhexidine gluconate Other / unclassified 0.2 % Topical
Subject Chlorhexidine gluconate Other / unclassified 10 ml Topical
Subject Lactobacillus paracasei Unknown Topical