drugset / Trial / NCT03009526
Efficacy and Safety of IPTp-DP Versus IPTp-SP in Malawi
Phase 3
Completed
602 enrolled
Kamuzu University of Health Sciences
Centers for Disease Control and Prevention · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
This study aims to compare the efficacy of monthly IPTp-DP with monthly IPTp-SP to determine if IPTp-DP is associated with a reduction in malaria infection at delivery among HIV-negative women in an area with high levels of SP resistance in Malawi.
Timeline
- Start
- 2017-01-17
- Primary completion
- 2018-10-24
- Completion
- 2018-10-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dihydroartemisinin-piperaquine | Unknown | 40 mg | — |
| Subject | Dihydroartemisinin-piperaquine | Unknown | 320 mg | — |
| Comparator | Sulfadoxine-pyrimethamine | Small molecule | 25 mg | — |
| Comparator | Sulfadoxine-pyrimethamine | Small molecule | 500 mg | — |