drugset / Trial / NCT03009526

Efficacy and Safety of IPTp-DP Versus IPTp-SP in Malawi

NCT03009526

RandomizedParallel-groupOpen-labelPrevention

Summary

This study aims to compare the efficacy of monthly IPTp-DP with monthly IPTp-SP to determine if IPTp-DP is associated with a reduction in malaria infection at delivery among HIV-negative women in an area with high levels of SP resistance in Malawi.

Timeline

Start
2017-01-17
Primary completion
2018-10-24
Completion
2018-10-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Dihydroartemisinin-piperaquine Unknown 40 mg
Subject Dihydroartemisinin-piperaquine Unknown 320 mg
Comparator Sulfadoxine-pyrimethamine Small molecule 25 mg
Comparator Sulfadoxine-pyrimethamine Small molecule 500 mg