drugset / Trial / NCT03015896

Nivolumab and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

NCT03015896 ↗

Phase 1/2 Active not recruiting 36 enrolled David Bond, MD Bristol-Myers Squibb · collab
NaSingle-groupOpen-labelTreatment

Summary

This I/II trial studies the side effects and best dose of lenalidomide when given together with nivolumab and to see how well they work in treating patients with non-Hodgkin or Hodgkin lymphoma that has come back and does not respond to treatment. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Drugs used in chemotherapy, such as lenalidomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving nivolumab and lenalidomide may work better in treating patients with non-Hodgkin or Hodgkin lymphoma.

Timeline

Start
2017-02-14
Primary completion
2026-08-09
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Lenalidomide Other / unclassified — Oral
Subject Nivolumab Monoclonal antibody — Intravenous