The Study of Two Different Chinese Traditional Medicine Treatment on Chronic Hepatitis B
Summary
Although the incidence of Hepatitis B has been decreased a lot recently years, there are still quite a few chronic hepatitis B patients in China. The anti-virus drugs of western medicine such as Entecavir and Tenofovir have been proved effective on decreasing the serum hepatitis B virus (HBV) level, on the other hand, Chinese materia medica showed effective on TCM syndromes of chronic hepatitis B (CHB) such as hypochondriac pain, jaundice and abdominal mass. Besides, the hepatic fibrosis could be delayed after the appropriate treatment of TCM. This study is a multicenter, randomized, open label, parallel group clinical trial to evaluate the efficacy of two different traditional Chinese medicine (TCM) herbal treatment on chronic hepatitis B.
Timeline
- Start
- 2017-01
- Primary completion
- 2017-10
- Completion
- 2017-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Chaihu Shugan San | Traditional medicine (herbal / TCM) | — | — |
| Comparator | Fuzilizhong Decoction | Traditional medicine (herbal / TCM) | — | — |
| Comparator | Ganlu Detoxification Pill | Traditional medicine (herbal / TCM) | — | — |
| Comparator | Ge Xia Zhu Yu Decoction | Traditional medicine (herbal / TCM) | — | — |
| Subject | Guifu Erxian Decoction | Traditional medicine (herbal / TCM) | — | — |
| Comparator | Jinkui Shenqi Bolus | Traditional medicine (herbal / TCM) | — | — |
| Subject | Soothe the liver and regulate qi Decoction | Traditional medicine (herbal / TCM) | — | — |
| Subject | Supplemented Ganbi Decoction | Traditional medicine (herbal / TCM) | — | — |
| Subject | Supplemented Ganji Decoction | Traditional medicine (herbal / TCM) | — | — |
| Subject | Supplemented Taohong Huazhuo Decoction | Traditional medicine (herbal / TCM) | — | — |
| Subject | Supplemented Zimu Dan | Traditional medicine (herbal / TCM) | — | — |
| Comparator | Xiaoyao powder | Traditional medicine (herbal / TCM) | — | — |
| Comparator | Yiguan Decoction | Traditional medicine (herbal / TCM) | — | — |
| Comparator | Yinchengao Decoction | Traditional medicine (herbal / TCM) | — | — |
| Background | Entecavir | Small molecule | — | — |
| Background | Tenofovir | Small molecule | — | — |