drugset / Trial / NCT03020004

Efficacy and Safety of Danoprevir/r + PR 12-week Triple Therapy in Treatment-Naive, Non-Cirrhotic, G1 CHC China II

NCT03020004

Phase 2 Completed 70 enrolled Ascletis Pharmaceuticals Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the Efficacy, Safety and Pharmacokinetics of Ritonavir-boosted Danoprevir (ASC08) in Combination with Peg-IFN and RBV in Treatment-Naive Non-Cirrhotic Patients Who Have Chronic Hepatitis Genotype 1.

Timeline

Start
2016-01
Primary completion
2016-11
Completion
2017-02

Drugs

EvaluationDrugModalityDoseRoute
Subject danoprevir Small molecule 100 mg Oral
Background PegIFN subcutaneous injection at 180 mcg weekly Unknown 180 ug Subcutaneous
Background Ribavirin Small molecule 1000 mg Oral
Background Ribavirin Small molecule 1200 mg Oral
Background Ritonavir Other / unclassified 100 mg Oral