drugset / Trial / NCT03025906
Phenobarbital Versus Valproate for Generalized Convulsive Status Epilepticus
RandomizedParallel-groupSingle-blindTreatment
Summary
Although generalized convulsive status epilepticus (GCSE) is a life-threatening emergency, evidence-based data to guide initial drug treatment choices are lacking in the Chinese population. The investigators conduct this prospective randomized controlled trial to evaluate the relative efficacy and safety of intravenous (IV) phenobarbital (PB) and valproate (VPA) in patients with GCSE.
Timeline
- Start
- 2017-02-16
- Primary completion
- 2019-10
- Completion
- 2019-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Phenobarbital | Unknown | 100 mg | Intravenous |
| Subject | Valproate | Small molecule | 1 mg/kg | Intravenous |
| Subject | Valproate | Small molecule | 2 mg/kg | Intravenous |