drugset / Trial / NCT03026166

A Study of Rovalpituzumab Tesirine Administered in Combination With Nivolumab and With or Without Ipilimumab for Adults With Extensive-Stage Small Cell Lung Cancer

NCT03026166

Phase 1/2 Terminated 42 enrolled AbbVie Bristol-Myers Squibb · collab
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to assess the safety and efficacy of rovalpituzumab tesirine administered in combination with nivolumab or nivolumab and ipilimumab in participants with extensive-stage small cell lung cancer (SCLC).

Timeline

Start
2017-03-30
Primary completion
2019-07-03
Completion
2019-07-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Ipilimumab Monoclonal antibody 1 mg/kg Intravenous
Subject Ipilimumab Monoclonal antibody 3 mg/kg Intravenous
Subject Nivolumab Monoclonal antibody 480 mg Intravenous
Subject Rovalpituzumab tesirine Other / unclassified 0.3 mg/kg Intravenous