drugset / Trial / NCT03043807
A Study of Definitive Therapy to Treat Prostate Cancer After Prostatectomy
NaSingle-groupOpen-labelTreatment
Summary
To assess the safety of treating men with oligometastatic prostate cancer with the following therapy: (1st) Systemic chemo-hormonal therapy with up to 6-months (\~24 weeks) of adjuvant androgen deprivation and up to 6 cycles of chemotherapy, (2nd) definitive local tumor control with adjuvant radiation therapy, and (3rd) consolidative stereotactic radiation to oligometastatic lesions. The men will receive a total of 2 years of androgen deprivation. Androgen blockade will be the same throughout the course of treatment.
Timeline
- Start
- 2017-02-22
- Primary completion
- 2022-10-17
- Completion
- 2022-10-17
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Abiraterone acetate | Small molecule | 1000 mg | — |
| Subject | Bicalutamide | Other / unclassified | 50 mg | Oral |
| Subject | Docetaxel | Small molecule | 75 mg/m2 | Intravenous |
| Subject | Leuprolide | Other / unclassified | 22.5 mg | Intramuscular |