drugset / Trial / NCT03059355
Infusion of Umbilical Cord Versus Bone Marrow Derived Mesenchymal Stem Cells to Evaluate Cytokine Suppression.
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study is to compare the safety and efficacy of UCMSCs and BMMSCs administered intravenously in patients to evaluate cytokine suppression in patients with chronic inflammation. Cells administered via intravenous infusion (IV) and will be tested in 37 patients in two phases (Pilot and Randomized).
Timeline
- Start
- 2018-04-12
- Primary completion
- 2020-03-23
- Completion
- 2021-02-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BM-MSCs | Cell therapy | 2e+07 cells | Intravenous |
| Subject | BM-MSCs | Cell therapy | 1e+08 cells | Intravenous |
| Subject | mesenchymal stem cells | Cell therapy | 2e+07 cells | Intravenous |
| Subject | mesenchymal stem cells | Cell therapy | 1e+08 cells | Intravenous |