Continuous Infusion Versus Intermittent Bolus Injection of Rocuronium

Summary

The research is to find out whether continuous infusion of rocuronium requires more or less amount of rocuronium, per kilogram and per hour, than bolus administered rocuronium during noncardiac surgery.

Timeline

Start

2017-03-23

Primary completion

2017-11

Completion

2018-03

Outcome

Met primary endpoint

paper CONCLUSION: In children undergoing general anaesthesia, the dose of rocuronium given by continuous administration was less than that with intermittent bolus. PMID 30540640 ↗

paper and 4.9 (1.0), (95% CI 4.6 to 5.3) μg kg min in the continuous infusion group (P = 0.001). PMID 30540640 ↗

Publications

• Choi SN, Jang YE, Lee JH, Kim EH, Kim JT, Kim HS. Comparison of rocuronium requirement in children with continuous infusion versus intermittent bolus: A randomised controlled trial. Eur J Anaesthesiol. 2019 Mar;36(3):194-199. doi: 10.1097/EJA.0000000000000934.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Rocuronium	Other / unclassified	—	—

Indications

No indication recorded.