drugset
drugset / Trial / NCT03069950

Study of Chemotherapy With or Without Hepatic Arterial Infusion for Patients With Unresectable Metastatic Colorectal Cancer to the Liver

NCT03069950 ↗

Phase 2 Withdrawn Memorial Sloan Kettering Cancer Center Oregon Health and Science University · collabQueens Cancer Center of Queens Hospital · collabThe Cleveland Clinic · collabWashington University School of Medicine · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to see if patients treated with both regional chemotherapy using the HAI pump and intravenous chemotherapy are able to have their liver tumors removed surgically (resected), versus treatment with only intravenous chemotherapy.

Timeline

Start
2017-02-28
Primary completion
2019-05-16
Completion
2019-05-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Floxuridine Unknown — Other
Subject fluorouracil Small molecule 1000 mg/m2 —
Subject fluorouracil Small molecule 1200 mg/m2 —
Background Dexamethasone Small molecule 25 mg Other
Background Irinotecan Small molecule 150 mg/m2 Intravenous
Background Leucovorin Small molecule 400 mg/m2 Intravenous
Background Panitumumab Monoclonal antibody 6 mg/kg Intravenous

Indications

colorectal adenocarcinoma