The Efficacy of a Dentifrice in Providing Relief From Immediate and Short Term Relief From Dentinal Hypersensitivity

Summary

A randomised, examiner blind, two treatment arm, stratified, parallel design, single-site study in subjects with at least two sensitive teeth to compare the efficacy of a test dentifrice against that of a control dentifrice in reducing dentinal hypersensitivity.

Timeline

Start

2012-03-01

Primary completion

2012-06-01

Completion

2012-06-12

Outcome

Missed primary endpoint

registry analysis (superiority or other test); Experimental Dentifrice vs Reference Dentifrice; p = 0.1774; Least square (LS) mean difference -0.19 (95% CI -0.46 to 0.09); ANCOVA; NCT03072719 ↗

Publications

• Parkinson CR, Hughes N, Hall C, Whelton H, Gallob J, Mason S. Three randomized clinical trials to assess the short-term efficacy of anhydrous 0.454% w/w stannous fluoride dentifrices for the relief of dentin hypersensitivity. Am J Dent. 2016 Feb;29(1):25-32.

Drugs

Indications