drugset / Trial / NCT03073850

Antithrombotic Treatment in Patients With Effectively Maintained Sinus Rhythm After Atrial Fibrillation Ablation

NCT03073850 ↗

Phase 4 Terminated 48 enrolled Korea University Guro Hospital
RandomizedParallel-groupOpen-labelPrevention

Summary

The purpose of the study is to investigate the best strategy for long-term stroke prevention in patients who have sinus rhythm after a successful catheter ablation for atrial fibrillation (AF) and who are at risk of thromboembolic events (CHA2DS2-VASc score ≥2). The investigators are going to compare antiplatelet therapy to oral anticoagulation (OAC) with different doses of edoxaban (30mg and 60mg).

Timeline

Start
2017-02-23
Primary completion
2019-12-15
Completion
2019-12-15

Outcome

Outcome not reported

Stopped (Enrollment): “Majority of enrolled patients have withdrawn.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Aspirin Small molecule 100 mg —
Subject Clopidogrel Small molecule 75 mg —
Subject Edoxaban Small molecule 15 mg Oral
Subject Edoxaban Small molecule 30 mg Oral
Subject Edoxaban Small molecule 60 mg Oral

Indications