drugset / Trial / NCT03081897

Regional Anaesthesia and Substance P in Head and Neck Cancer

NCT03081897 ↗

Suspended 40 enrolled Charite University, Berlin, Germany
RandomizedParallel-groupOpen-labelSupportive care

Summary

In the clinical trial the investigators will observe the impact of regional anesthesia in addition to a general anesthesia on the expression of substance P in patients with unilateral Head or Neck cancer undergoing unilateral Neck Dissection. The investigators will perform an unilateral regional cervical plexus block on the tumor side. The tissue of the tumor side will be analysed by immunohistology, measuring the expression of the Substance P.

Timeline

Start
2016-07
Primary completion
2023-07-01
Completion
2023-07-01

Outcome

Outcome not reported

Stopped: “for organizational reasons”

Drugs

EvaluationDrugModalityDoseRoute
Subject Ropivacaine Other / unclassified 0.75 % Other
Background Propofol Small molecule 2 mg/kg —
Background Remifentanil Small molecule 0.1 ug/kg —
Background Remifentanil Small molecule 0.4 ug/kg —

Indications