drugset / Trial / NCT03086733

Phase II Lung Metcore - Preoperative Metformin for Lung Cancer

NCT03086733 ↗

Phase 2 Completed 28 enrolled University Health Network, Toronto
NaSingle-groupOpen-labelTreatment

Summary

This is a phase II single centre open label single arm pre-operative window of metformin treatment in stage I-IIIa Non small cell lung cancer. In which patients will be invited to participate by receiving Metformin treatment during 14 to 21 days at 850 mg BID until the day before surgery. They will be followed closely for any Adverse Events during treatment and 30 days after surgery. During treatment there will be no follow up tests except 1 fasting blood glucose at week 2 of treatment. Survival data will be prospectively gathered after study treatment has ended until death.

Timeline

Start
2016-12-05
Primary completion
2020-07
Completion
2020-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 850 mg Oral