drugset / Trial / NCT03088124

Active Surveillance With or Without Apalutamide Treatment in Low Risk Prostate Cancer

NCT03088124

RandomizedParallel-groupOpen-labelTreatment

Summary

Many prostate cancer are slow or non progressive forms that would never impair quality or quantity of like of life if undetected. For this localized prostate cancer, the recommendation is an active surveillance, however often experienced by the patient as a lack of care. Thus the introduction of new potent androgen receptor inhibitor raise the question of the benefit of early hormonal therapy in localized prostate cancers. The aim of this study is to assess whether treatment with an oral androgen receptor inhibitor could influence the progression of localized prostate cancer and delay the time to local treatment initiation.

Timeline

Start
2017-04-28
Primary completion
2024-10-08
Completion
2024-10-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Apalutamide Small molecule 240 mg Oral

Indications

No indication recorded.