drugset / Trial / NCT03089333
Effects of SGLT2 Inhibitor on Hemodynamic Parameters in Resistant Hypertensive Subjects
Phase 4
Completed
16 enrolled
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo · collab
RandomizedCrossoverSingle-blindTreatment
Summary
New strategies trying to achieve blood pressure control and consequently reduce cardiovascular risk in resistant hypertensive subjects are promising. In this context, the SGLT2 inhibitor dapagliflozin, not yet investigated in resistant hypertension, arises as a potential drug in order to impact on blood pressure levels, as well as target organ damage and adiposity in this high-risk population.
Timeline
- Start
- 2016-07
- Primary completion
- 2017-10
- Completion
- 2017-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dapagliflozin | Small molecule | 10 mg | — |
| Subject | Glyburide | Small molecule | 5 mg | — |