drugset / Trial / NCT03092453

Dendritic Cell Vaccination in Patients With Advanced Melanoma

NCT03092453 ↗

Phase 1 Completed 5 enrolled University of Pennsylvania
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to investigate a method of using dendritic cells (a kind of white blood cell) as a vaccine to stimulate your own immune system to react to your melanoma cells.

Timeline

Start
2017-05-01
Primary completion
2023-03-31
Completion
2023-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Mature dendritic cell (DC) vaccine Vaccine 1e+06 cells —
Subject Mature dendritic cell (DC) vaccine Vaccine 5e+06 cells —
Background Cyclophosphamide Other / unclassified 300 mg/m2 Intravenous
Background Pembrolizumab Monoclonal antibody — —

Indications