Study of Topical SOR007 Ointment for Cutaneous Metastases

Summary

This study evaluates a topical nanoparticle paclitaxel ointment (SOR007) for the treatment of cutaneous metastases from non-melanoma cancer in adults. Three concentrations of SOR007 will be evaluated in dose-rising cohorts of three. An expanded cohort will treat additional subjects at the maximum tolerated dose.

Timeline

Start

2018-01-31

Primary completion

2020-04-29

Completion

2020-04-29

Publications

• Lacouture ME, Goldfarb SB, Markova A, Chawla SP, Dewnani K, Iacobucci M, Lang JE. Phase 1/2 study of topical submicron particle paclitaxel for cutaneous metastases of breast cancer. Breast Cancer Res Treat. 2022 Jul;194(1):57-64. doi: 10.1007/s10549-022-06584-6. Epub 2022 Apr 26.

Drugs

Indications