drugset / Trial / NCT03107858

The Effect of Norepinephrine Versus Dopamine in Renal Transplant Recipients on Postoperative Graft Function

NCT03107858

Phase 2/3 Unknown 44 enrolled Assiut University
RandomizedParallel-groupDouble-blindPrevention

Summary

Renal transplantation is now recognized as a treatment of choice for patients with chronic renal failure with end-stage renal disease. Renal transplantations are associated with better quality of life, better cost/benefit ratio, and possibly longer survival. Significant changes in blood pressure are common throughout the surgical procedure for kidney transplantation. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration.

Timeline

Start
2017-11-01
Primary completion
2019-01-01
Completion
2019-11-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dopamine Small molecule 5 ug/kg
Comparator Dopamine Small molecule 15 ug/kg
Comparator Norepinephrine Other / unclassified 0.05 ug/kg
Comparator Norepinephrine Other / unclassified 0.15 ug/kg

Indications

No indication recorded.