drugset / Trial / NCT03119623
Comparing ARNI With ACE Inhibitor on Endothelial Function
RandomizedParallel-groupTriple-blindTreatment
Summary
PARADOR is multisite, randomized, double-blind, phase IV clinical trial to compare the effect of sacubitril/valsartan (Entresto™) to enalapril (Vasotec®) on blood vessel function in subjects with heart failure with reduced ejection fraction (HFREF).
Timeline
- Start
- 2017-06-01
- Primary completion
- 2019-08
- Completion
- 2019-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Enalapril | Other / unclassified | 10 mg | Oral |
| Comparator | sacubitril/valsartan | Other / unclassified | 200 mg | Oral |