drugset / Trial / NCT03119831
Effectiveness of Three Different Mouthrinses in Dental Plaque Control and Early Wound Healing
RandomizedParallel-groupQuadruple-blindSupportive care
Summary
Aim: This study compared the effectiveness of three different mouthrinses (alcohol and non-alcohol chlorhexidine, alkyl dimethyl glycine / alkyl dimethyl amine oxide - C31G) in plaque control and early wound healing, postoperatively. Materials and Methods: In this, randomized, double-blind, controlled clinical trial 42 patients were allocated to three groups assigned to two weeks rinsing after periodontal surgery with C31G (group A), alcohol-free chlorhexidine 0.12% (group B) or alcohol-based chlorhexidine 0.12% (group C). At weeks 1 and 2, plaque and early wound healing indices were recorded. At day 14, total bacterial counts were estimated utilizing real - time qPCR. Statistics included linear and generalized linear mixed models.
Timeline
- Start
- 2015-11
- Primary completion
- 2016-07
- Completion
- 2016-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | C31G | Unknown | 15 ml | Oral |
| Subject | Chlorhexidine gluconate | Other / unclassified | 0.12 % | Oral |
| Subject | Chlorhexidine gluconate | Other / unclassified | 15 ml | Oral |