drugset / Trial / NCT03119831

Effectiveness of Three Different Mouthrinses in Dental Plaque Control and Early Wound Healing

NCT03119831

RandomizedParallel-groupQuadruple-blindSupportive care

Summary

Aim: This study compared the effectiveness of three different mouthrinses (alcohol and non-alcohol chlorhexidine, alkyl dimethyl glycine / alkyl dimethyl amine oxide - C31G) in plaque control and early wound healing, postoperatively. Materials and Methods: In this, randomized, double-blind, controlled clinical trial 42 patients were allocated to three groups assigned to two weeks rinsing after periodontal surgery with C31G (group A), alcohol-free chlorhexidine 0.12% (group B) or alcohol-based chlorhexidine 0.12% (group C). At weeks 1 and 2, plaque and early wound healing indices were recorded. At day 14, total bacterial counts were estimated utilizing real - time qPCR. Statistics included linear and generalized linear mixed models.

Timeline

Start
2015-11
Primary completion
2016-07
Completion
2016-07

Drugs

EvaluationDrugModalityDoseRoute
Subject C31G Unknown 15 ml Oral
Subject Chlorhexidine gluconate Other / unclassified 0.12 % Oral
Subject Chlorhexidine gluconate Other / unclassified 15 ml Oral

Indications