Prophylactic Topical Epinephrine to Reduce Bleeding in Transbronchial Lung Biopsies

Summary

Bleeding poses potential for significant complication after transbronchial lung biopsies. The investigators hypothesize that prophylactic intrabronchial instillation of topical epinephrine will reduce the likelihood of bleeding. The investigators plan a double-blind, placebo controlled trial to evaluate this hypothesis.

Timeline

Start

2017-07-01

Primary completion

2021-07-02

Completion

2021-07-02

Outcome

Met primary endpoint

paper 4 cases (8%) in the prophylactic epinephrine group and in 13 cases (24%) in the control group (p = 0.04). PMID 37140517 ↗

Publications

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Drugs

Indications