drugset / Trial / NCT03127631
A Study for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients
Active not recruiting
5000 enrolled
McMaster University
Canadian Cancer Society (CCS) · collabProstate Cancer Canada · collabTolmar Inc. · collab
RandomizedFactorialOpen-labelTreatment
Summary
RADICAL PC1 is a prospective cohort study of men with a new diagnosis of prostate cancer. RADICAL PC2 is a randomized, controlled trial of a systematic approach to modifying cardiovascular and lifestyle risk factors in men with a new diagnosis of prostate cancer.
Timeline
- Start
- 2015-10-21
- Primary completion
- 2026-12-31
- Completion
- 2026-12-31
Publications
- Dahan J, Pinthus J, Delouya G, Taussky D, Duceppe E, de Jesus A, Leong D. Investigation of association between clinically significant prostate cancer, obesity and platelet to-lymphocyte ratio and neutrophil -to-lymphocyte ratio. BMC Urol. 2024 Oct 16;24(1):226. doi: 10.1186/s12894-024-01617-2.
- Savija N, Leong DP, Pinthus J, Karampatos S, Shayegan B, Mian R, Rangarajan S, Fradet V, de Souza RJ, Mente A, Dehghan M. Development and Comparability of a Short Food-Frequency Questionnaire to Assess Diet in Prostate Cancer Patients: The Role of Androgen Deprivation Therapy in CArdiovascular Disease - A Longitudinal Prostate Cancer Study (RADICAL PC) Substudy. Curr Dev Nutr. 2021 Aug 12;5(11):nzab106. doi: 10.1093/cdn/nzab106. eCollection 2021 Nov.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atorvastatin | Small molecule | — | — |
| Comparator | Pravastatin | Small molecule | — | — |
| Comparator | Rosuvastatin | Small molecule | — | — |
| Comparator | Simvastatin | Small molecule | — | — |