drugset / Trial / NCT03139370
Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers
NaSingle-groupOpen-labelTreatment
Summary
The primary objectives of Phase 1A are to evaluate the safety of KITE-718, determine a recommended Phase 1B dose, and to evaluate the efficacy of KITE-718 in Phase 1B.
Timeline
- Start
- 2017-12-27
- Primary completion
- 2021-06-30
- Completion
- 2023-06-04
Outcome
Outcome not reported
Stopped: “The study was terminated due to the sponsor's decision to discontinue the clinical trial.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | KITE-718 | Cell therapy | — | — |
| Background | Cyclophosphamide | Other / unclassified | — | Intravenous |
| Background | Fludarabine | Small molecule | — | Intravenous |