drugset / Trial / NCT03142607
Comparative Evaluation of Chlorhexidine, Metronidazole and Combination Gels on Gingivitis
RandomizedFactorialQuadruple-blindTreatment
Summary
Patient presenting to the dental clinic with gingivitis and fulfilling the inclusion criteria will be included in the study after taking informed consent. Participants will be divided into three groups. Each group will be instructed to apply metronidazole gel, chlorhexidine gel or combination of metronidazole and chlorhexidine gel on the marginal gingiva. Measurement for the gingival index will be taken at baseline, at 2 weeks and at 4 weeks interval
Timeline
- Start
- 2017-02-03
- Primary completion
- 2018-01-02
- Completion
- 2018-02-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Chlorhexidine | Small molecule | 0.2 % | Topical |
| Comparator | Metronidazole | Small molecule | 0.8 % | Topical |
| Comparator | Metronidazole | Small molecule | 1 % | Topical |