drugset / Trial / NCT03142607

Comparative Evaluation of Chlorhexidine, Metronidazole and Combination Gels on Gingivitis

NCT03142607

Phase 3 Unknown 90 enrolled Aga Khan University
RandomizedFactorialQuadruple-blindTreatment

Summary

Patient presenting to the dental clinic with gingivitis and fulfilling the inclusion criteria will be included in the study after taking informed consent. Participants will be divided into three groups. Each group will be instructed to apply metronidazole gel, chlorhexidine gel or combination of metronidazole and chlorhexidine gel on the marginal gingiva. Measurement for the gingival index will be taken at baseline, at 2 weeks and at 4 weeks interval

Timeline

Start
2017-02-03
Primary completion
2018-01-02
Completion
2018-02-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Chlorhexidine Small molecule 0.2 % Topical
Comparator Metronidazole Small molecule 0.8 % Topical
Comparator Metronidazole Small molecule 1 % Topical

Indications