drugset / Trial / NCT03149159

Investigator-Initiated Trial of Combined Ipilimumab, Nivolumab and Stereotactic Radiation in Patients With Metastatic Clear-Cell RCC (ccRCC) Who Have Failed Treatment With Single-Agent Nivolumab

NCT03149159 ↗

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to see if continued nivolumab with the addition of ipilimumab plus hypo-fractionated stereotactic radiation (sTR) of a single lesions results in partial or complete responses in patients with metastatic ccRCC who fail initial treatment with single agent nivolumab.

Timeline

Start
2018-04-01
Primary completion
2018-04-01
Completion
2018-04-01

Outcome

Outcome not reported

Stopped: “This study is withdrawn due to feasibility issues.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Ipilimumab Monoclonal antibody 1 mg/kg —
Subject Nivolumab Monoclonal antibody 240 mg —