drugset / Trial / NCT03159754

Optimal Care of Complicated Appendicitis

NCT03159754

Phase 4 Completed 40 enrolled University of Michigan
Non-randomizedParallel-groupOpen-labelTreatment

Summary

When the appendix becomes infected and inflamed, it is called appendicitis. Sometimes, if the infection and inflammation get worse, the appendix can die or burst, leading to a larger infection or even pus pockets around the appendix. This is called complicated, or perforated, appendicitis. Three common treatments for complicated appendicitis are * appendectomy (removal of the appendix) right away * appendectomy several weeks after the diagnosis * treating the appendicitis without performing an appendectomy This study seeks to determine which of these three approaches is most cost-effective in children with complicated appendicitis.

Timeline

Start
2017-06-29
Primary completion
2020-03-26
Completion
2020-03-26

Drugs

EvaluationDrugModalityDoseRoute
Background Ciprofloxacin Small molecule
Background Metronidazole Small molecule
Background piperacillin/tazobactam Unknown

Indications