drugset / Trial / NCT03159754
Optimal Care of Complicated Appendicitis
Non-randomizedParallel-groupOpen-labelTreatment
Summary
When the appendix becomes infected and inflamed, it is called appendicitis. Sometimes, if the infection and inflammation get worse, the appendix can die or burst, leading to a larger infection or even pus pockets around the appendix. This is called complicated, or perforated, appendicitis. Three common treatments for complicated appendicitis are * appendectomy (removal of the appendix) right away * appendectomy several weeks after the diagnosis * treating the appendicitis without performing an appendectomy This study seeks to determine which of these three approaches is most cost-effective in children with complicated appendicitis.
Timeline
- Start
- 2017-06-29
- Primary completion
- 2020-03-26
- Completion
- 2020-03-26
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Ciprofloxacin | Small molecule | — | — |
| Background | Metronidazole | Small molecule | — | — |
| Background | piperacillin/tazobactam | Unknown | — | — |