drugset / Trial / NCT03169348
The Effect of Direct Antiviral Therapy on Hepatitis c Virus-related Thrombocytopenia
NaSingle-groupOpen-labelTreatment
Summary
Autoimmune thrombocytopenic purpura is an immunological disorder characterized by increased platelet destruction due to presence of anti-platelet antibodies. Hepatitis C virus infection, which is one of the most common chronic viral infections worldwide, may cause secondary chronic immune thrombocytopenic purpura. It seemed to play a pathogenic role in autoimmune thrombocytopenic purpura. Moreover, the successful response (negative hepatitis C virus - ribonucleic acid) to tapered steroids and antiviral therapy was useful to revert thrombocytopenia
Timeline
- Start
- 2017-11-01
- Primary completion
- 2019-06
- Completion
- 2019-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Daclatasvir | Small molecule | — | Oral |
| Subject | Ledipasvir/sofosbuvir | Unknown | — | Oral |
| Subject | Sofosbuvir | Small molecule | — | Oral |