drugset / Trial / NCT03169985
Randomized Controlled Trial of Moderate-Intensity Rosuvastatin With Ezetimibe Combination Therapy Versus High-Intensity Rosuvastatin on Progression of Coronary Atherosclerotic Plaque
Phase 4
Active not recruiting
280 enrolled
Samsung Medical Center
Hanmi Pharmaceutical Company Limited · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
The aim of this prospective, open-label, randomized, single center study is to compare the effect of usual dose rosuvastatin plus ezetimibe and high-dose rosuvastatin on modifying atherosclerotic plaque.
Timeline
- Start
- 2017-07-12
- Primary completion
- 2027-01-28
- Completion
- 2027-01-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ezetimibe | Unknown | 10 mg | Oral |
| Comparator | Rosuvastatin | Small molecule | 10 mg | Oral |
| Comparator | Rosuvastatin | Small molecule | 20 mg | Oral |