Effect of Deep Versus Moderate Neuromuscular Block During Sevoflurane Anesthesia on Intraoperative Surgical Conditions.

Summary

A deep neuromuscular block (NMB) is often associated with improved surgical conditions especially in laparoscopic surgery. We previously showed that deep NMB is superior to a moderate NMB under propofol anesthesia. However, this may not apply to sevoflurane anesthesia and sevoflurane by itself produces some degree of muscle relaxation. We therefore plan to investigate the effect of deep NMB on surgical conditions under sevoflurane anesthesia maintenance.

Timeline

Start

2017-06-14

Primary completion

2020-04-01

Completion

2020-06-01

Outcome

Missed primary endpoint

registry analysis (superiority test); Deep Neuromuscular Block; p = 0.94; GEEGLM NCT03170661 ↗

Drugs

Indications

No indication recorded.