drugset / Trial / NCT03171740

Premedication With Intranasal Dexmedetomidine or Midazolam for Prevention of Emergence Agitation in Children

NCT03171740

Phase 3 Completed 22 enrolled Brasilia University Hospital
RandomizedParallel-groupQuadruple-blindPrevention

Summary

Study where children will receive one premedication, either intranasal dexmedetomidine or oral midazolam, to reduce agitation on emergence of anesthesia. The hypothesis is that dexmedetomidine is superior but previous studies lack quality.

Timeline

Start
2017-06-01
Primary completion
2017-12-01
Completion
2018-01-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexmedetomidine Other / unclassified 1 ug/kg Intranasal
Comparator Midazolam Small molecule 0.5 mg/kg Oral

Indications