Pharmacokinetics Distribution of Raltegravir by PET/MR

Summary

This is a single-center drug distribution and pharmacokinetic study of a single microdose of 18F-raltegravir given to 10 HIV-infected subjects who are either taking or not taking a raltegravir-containing ART regimen. After administration of IV 18F-raltegravir, subjects will undergo PET/MRI in order to determine the distribution of radiolabeled drug through the lymphoreticular system and other tissues throughout the entire body.

Timeline

Start

2018-04-01

Primary completion

2024-11-01

Completion

2025-01-01

Drugs

Indications