drugset / Trial / NCT03181308

Study of Carotuximab (TRC105) Plus Nivolumab in Patients With Metastatic NSCLC

NCT03181308

Phase 1 Completed 11 enrolled Tracon Pharmaceuticals Inc.
NaSingle-groupOpen-labelTreatment

Summary

This is a multi-center, open-label, nonrandomized, dose-escalation, Phase 1b study of carotuximab in combination with standard dose nivolumab in patients with NSCLC that has progressed on or after platinum-based chemotherapy or PD-1/PD-L1 checkpoint inhibition, as a single agent or with chemotherapy.

Timeline

Start
2017-11-09
Primary completion
2019-07-22
Completion
2019-07-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Carotuximab Monoclonal antibody
Background Nivolumab Monoclonal antibody