drugset / Trial / NCT03181308
Study of Carotuximab (TRC105) Plus Nivolumab in Patients With Metastatic NSCLC
NaSingle-groupOpen-labelTreatment
Summary
This is a multi-center, open-label, nonrandomized, dose-escalation, Phase 1b study of carotuximab in combination with standard dose nivolumab in patients with NSCLC that has progressed on or after platinum-based chemotherapy or PD-1/PD-L1 checkpoint inhibition, as a single agent or with chemotherapy.
Timeline
- Start
- 2017-11-09
- Primary completion
- 2019-07-22
- Completion
- 2019-07-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carotuximab | Monoclonal antibody | — | — |
| Background | Nivolumab | Monoclonal antibody | — | — |