Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique
Summary
* The teeth of the patients that meet inclusion criteria will be anesthetized, isolated with a rubber dam. * Cavity opened using conventional high-speed rotary instruments. * The central cariogenic biomass and the superficial parts of the necrotic dentine will be removed with round burs. * Caries lesion will be completely removed in the enamel/dentin junction. * The excavation procedure will be terminated as soon as the soft and wet dentine was removed and the remaining tissue was leathery but not hard on exploring. * A dentinal sample will then be collected from the base of the cavity using sterile spoon excavator as a baseline for bacteriological assessment. * Then, application of either intervention or control agent, another dentinal sample will be collected using a sterile excavator and transferred into sterile tubes and transferred to the laboratory for microbiological analysis. * Filling of the cavity with resin composite restoration. * All clinical procedures will be carried out at the same visit.
Timeline
- Start
- 2018-04-01
- Primary completion
- 2018-11-01
- Completion
- 2018-12-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Chlorhexidine | Small molecule | 10 mg | Topical |
| Subject | nanosilver fluoride | Unknown | 10 mg | Topical |