drugset / Trial / NCT03187912

Accelerated Corneal Cross-linking With Different Riboflavin Solutions

NCT03187912

Phase 3 Completed 60 enrolled Medical University of Vienna
RandomizedParallel-groupTriple-blindTreatment

Summary

Following the Bunsen-Roscoe law, accelerated cross-linking protocols with higher irradiation intensities and shorter irradiation times have been introduced. In addition, new riboflavin solutions with HPMC (hydroxylpropyl methylcellulose) instead of dextran found its way into CXL-treatment. The aim of this trial is to evaluate clinical outcomes in an accelerated corneal collagen cross-linking protocol with different riboflavin solutions.

Timeline

Start
2016-09-19
Primary completion
2020-03-30
Completion
2020-03-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Riboflavin Other / unclassified Other

Indications