drugset / Trial / NCT03197480
Diabetic Macular Edema Asian Response (DEAR) Study: Biomarkers for Response to Aflibercept in Asian Patients With Center Involving DME
Phase 4
Unknown
36 enrolled
Singapore National Eye Centre
Santen Pharmaceutical Co., Ltd. · collabSingapore Eye Research Institute · collab
NaSingle-groupOpen-labelTreatment
Summary
To investigate whether ocular imaging and proteomic biomarkers; and systemic biochemical, metabolomic, and genetic biomarkers predict treatment response to intravitreal aflibercept in a cohort of patients with DME.
Timeline
- Start
- 2019-04-17
- Primary completion
- 2020-12-31
- Completion
- 2021-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aflibercept | Protein / enzyme biologic | — | Intravitreal |