drugset / Trial / NCT03197493
Extension, Carbidopa-levodopa in Neovascular Age-related Macular Degeneration (AMD)
Phase 2
Completed
35 enrolled
Snyder, Robert W., M.D., Ph.D., P.C.
Snyder Biomedical Corporation · collab
NaSingle-groupOpen-labelTreatment
Summary
This protocol is an extension of protocol 0002, Proof of Concept and Dose Ranging Study of carbidopa-levodopa in Neovascular AMD. that is a 3 month study of escalating doses of carbidopa-levodopa in neovascular AMD. This trial is a 9 month extension for patients who successfully complete protocol 0002 and wish to continue carbidopa-levodopa therapy. It will use the two higher dose regimens of protocol 0002. these will be assigned according to how well the higher dose was tolerated in protocol 0002.
Timeline
- Start
- 2017-08-01
- Primary completion
- 2020-07-09
- Completion
- 2020-07-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carbidopa | Unknown | 25 mg | Oral |
| Subject | Carbidopa | Unknown | 50 mg | Oral |
| Subject | Levodopa | Small molecule | 100 mg | Oral |
| Subject | Levodopa | Small molecule | 200 mg | Oral |