drugset / Trial / NCT03197493

Extension, Carbidopa-levodopa in Neovascular Age-related Macular Degeneration (AMD)

NCT03197493

NaSingle-groupOpen-labelTreatment

Summary

This protocol is an extension of protocol 0002, Proof of Concept and Dose Ranging Study of carbidopa-levodopa in Neovascular AMD. that is a 3 month study of escalating doses of carbidopa-levodopa in neovascular AMD. This trial is a 9 month extension for patients who successfully complete protocol 0002 and wish to continue carbidopa-levodopa therapy. It will use the two higher dose regimens of protocol 0002. these will be assigned according to how well the higher dose was tolerated in protocol 0002.

Timeline

Start
2017-08-01
Primary completion
2020-07-09
Completion
2020-07-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Carbidopa Unknown 25 mg Oral
Subject Carbidopa Unknown 50 mg Oral
Subject Levodopa Small molecule 100 mg Oral
Subject Levodopa Small molecule 200 mg Oral